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Karen Palestini

Partner; Chair, Health Care Group
Primary Office
1500 Market St. 3500E
Philadelphia, PA 19102
Direct(215) 575-7171
Fax(215) 575-7200
99 Park Avenue
Suite 320
New York, NY 10016
Direct(917) 675-4257   
Fax(212) 208-6874
457 Haddonfield Rd., Suite 700
Cherry Hill, NJ 08002
Direct(856) 675-1957
Fax(856) 663-8855

Karen Palestini concentrates her practice on mergers, acquisitions and joint ventures, general corporate business matters, and regulatory compliance. While Karen's practice spans a variety of industries, she has particular experience in the healthcare, wellness, and education areas of commerce, assisting both for-profit and non-profit, tax-exempt organizations.

Karen has particular expertise with the formation, governance and operations of non-profit entities, both in furtherance of charitable purposes and in accordance with unrelated business income limitations and excess benefit prohibitions. Karen has also structured an impressive range of sophisticated transactions and affiliations between and among tax-exempt entities, public benefit entities, for-profit entities and third party donors, sponsors and contributors in the healthcare industry, academia and other fields of commerce.

Karen's clients include hospitals, ambulatory surgery centers, diagnostic testing facilities, pharmaceutical companies, physician practices, behavioral health centers, colleges, universities, foundations, organ procurement organizations, venture capital and private equity firms, group purchasing organizations, medical and scientific institutes, commercial lenders, home health agencies, urgent care centers, clinics, pharmacies, assisted living facilities, and wellness centers.

Representative Experience

  • Developed the organizational, funding and regulatory structure for a high-profile Mid-Atlantic neurosciences institute, involving a medical school, various regional hospitals, a multi-subspecialty physician network and a medical research foundation.
  • Formed one of the first 27 accountable care organizations ("ACOs") approved by CMS to participate in the Medicare Shared Savings Program in April 2012, involving a geographically diverse, multi-hospital healthcare system in partnership with a regional medical center and with participation from more than 1,300 physicians, including more than 200 primary care physicians, 50 nurse practitioners and 10 ancillary care providers serving patients in two states.
  • Negotiated the terms of a multi-million dollar infectious disease laboratory joint venture between a regional blood center and a prominent organ procurement organization.
  • Represented the surviving entity in the first conversion of a non-profit hospital to for-profit status in the state of New Jersey.
  • Coordinated the private placement of securities for, and assisted with the development of, a novel entity offering investors a vehicle for establishing a pre-ACO operational structure via a ‘roll up' of numerous primary care practices.
  • Conducted an extensive compliance plan review and analysis of a multi-provider medical center.
  • Developed HIPAA- and FERPA-compliant policies and procedures for large University with application to both its general student population and its health center.
  • Represented non-profit organization in internal investigation of alleged criminal misconduct by personnel.
  • Negotiated university-sports "team physician" agreements.
  • Facilitated various sports medicine joint ventures between professional practices/licensed professionals, universities, and academic medical centers.
  • Directed a number of university healthcare clinic arrangements and supervisory protocols and risk management assessments involving nursing students, physical therapy students, and other students majoring in the allied health sciences.

Professional & Community Activities

  • Member, American Health Lawyers Association
  • Honorary Trustee, Wills Eye Hospital Glaucoma Service Foundation
  • Trustee, Delaware River Recreation Foundation

Professional Recognition

  • Taught courses in Health Care Law, Health Care Transactions Health Care Ethics and Education Law at Seton Hall Law School and St. Joseph's University.
  • Served a federal clerkship with the Honorable Joseph L. McGlynn, Jr. of the U.S. District Court for the Eastern District of Pennsylvania.

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Alternate Biographies





  • J.D., Villanova University School of Law, 1990
    • Staff member, Villanova Law Review
    • Founding Editor-In-Chief, Villanova Environmental Law Journal
  • B.A., University of Delaware, 1987

Bar Admissions

  • Pennsylvania, 1990
  • New Jersey, 1990
  • New York, 2000